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小剂量反应停联合地塞米松治疗难治性多发性骨髓瘤的临床疗效观察 被引量:1

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摘要 目的:观察小剂量反应停联合地塞米松对难治性多发性骨髓瘤的疗效。方法:小剂量反应停联合地塞米松治疗难治性多发性骨髓瘤23例,治疗方法用反应停起始剂量100mg/d,2周后加量至200mg/d,每天分2次口服,地塞米松1.5mg/d,每天分2次口服,二药联合应用,持续3个月,3个月后进行化疗1个疗程,3个月为1个周期。结果:2个周期治疗后部分缓解7例,进步9例,无效7例,总有效率为70%。结论:小剂量反应停联合地塞米松治疗难治性多发性骨髓瘤疗效确切,不良反应少。
作者 杨国华
出处 《青海医药杂志》 2009年第12期16-17,共2页 Qinghai Medical Journal
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参考文献3

  • 1Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med, 1999,341(21) :1 565-1 571.
  • 2刘丽辉,武永吉.反应停治疗多发性骨髓瘤的机制及临床应用[J].临床血液学杂志,2002,15(3):138-139. 被引量:31
  • 3Palumbo A, Giaccone L, Bertola A ,et al. Low- dose thalidomide plus dexamethasone is an effective salvage therapy for advanced myeloma. Hematologica ,2001,86 (4) :399.

二级参考文献8

  • 1Bellamy W,List A,Grogan T.Expression of VEGF and its receptors in myeloma.Program and abstracts of the Ⅷinternational myeloma workshop[].Canada Reports.2001
  • 2Tosi P,Ronconi S,Zamagni E,et al.Salvage therapy with thalidomide in multiple myeloma patients relapsing after autologous peripheral blood stem cell transplantation[].Haematologica.2001
  • 3Rajkumar S V,Leong T,Roche P C,et al.Prognostic value of bone marrow angiogensis in multiple myeloma[].Clinical Cancer Research.2000
  • 4Schreiber S,Ackermann J,Obermair A,et al.Multiple myeloma with eletion of chromosome 13q is characterized by ineased bone marrow neovascularization[].British Journal of Haematology.2000
  • 5Peuckmann V,Fisch M,Bruera E,et al.Potential novel uses of thalidomide: focus on palliative care[].Drugs.2000
  • 6Celgene.Program and abstracts of the Ⅷinternational myeloma workshop[].Canada Reports.2001
  • 7Faith E D,Noopur R,Teru H,et al.Thalidomide and immunmodulatory derivatives augment natral killer cell cytotoxicity in multiple myeloma[].Blood.2001
  • 8Rajkumar S V,Witzig T E.A review of angiogenesis and antiangiogenic therapy with thalidomide in multiple myeloma[].Cancer Treatment Reviews.2000

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