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An Investigation into Disease Progression and the Correlation between Diabetes Mellitus and Hepatocellular Carcinoma

An Investigation into Disease Progression and the Correlation between Diabetes Mellitus and Hepatocellular Carcinoma
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摘要 Diabetes mellitus has been associated with anincreased risk of hepatocellular carcinoma in recent studies ofpatients. At the same time, advanced hepatocellular carcinomaitself can cause glucose intolerance and can aggravate diabetes.Diabetes mellitus inducing hepatocellular carcinoma may resultin changes in the following aspects: dysfunction of organism,endocrine hormone balance and interactions, endothelins andso on. One way, diabetes mellitus may induce hepatocellularcarcinoma through the effects of chemotherapeutics and otheradjuvant drugs. This review outlines the relationship betweendiabetes mellitus and the risk of hepatocellular carcinoma as wellas treatments for hepatocellular carcinoma, which may be helpfulfor clinicians. Diabetes mellitus has been associated with an increased risk of hepatocellular carcinoma in recent studies of patients. At the same time, advanced hepatocellular carcinoma itself can cause glucose intolerance and can aggravate diabetes. Diabetes mellitus inducing hepatocellular carcinoma may result in changes in the following aspects: dysfunction of organism, endocrine hormone balance and interactions, endothelins and so on. One way, diabetes mellitus may induce hepatocellular carcinoma through the effects of chemotherapeutics and other adjuvant drugs. This review outlines the relationship between diabetes mellitus and the risk of hepatocellular carcinoma as well as treatments for hepatocellular carcinoma, which may be helpful for clinicians.
出处 《Clinical oncology and cancer resexreh》 CAS CSCD 2009年第6期451-455,共5页 临床肿瘤与癌症研究(英文版)
关键词 糖尿病 肝癌 调查进展 疾病 内分泌激素 功能紊乱 相互作用 辅助治疗 diabetes mellitus, hepatocellular carcinoma, correlation.
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  • 1雷晓,余佩武,赵永亮,石彦,饶芸,曾冬竹,吴淼,周立新.CD4^+CD25^+调节性T细胞在胃癌患者的表达及其临床意义[J].第三军医大学学报,2006,28(5):397-400. 被引量:9
  • 2Khazaie K,van Boehmer H.The impact of CD4^+CD25^+ Treg on tumor specific CD8+T cell cytotoxicity and cancer[J].Semin Cancer Biol,2006,16(2):124-136.
  • 3Turk M J,Guevara-Patino J A,Rizzuto G A,et al.Concomitant tumor immunity to a poorly immuogenic melanoma is prevented by regulatory T cells[J].J Exp Med,2004,200(6):771-782.
  • 4Chakraborty N G,Chattopadhyay S,Mehrotra S,et al.Regulatory T-cell response and tumor vaccine-induced cytotoxic T lymphocytes in human melanoma[J].Hum Immunol,2004,65(8):794-802.
  • 5Sasada T,Kimura M,Yoshida Y,et al.CD4^+CD25^+ regulatory T cells in patients with gastrointestinal malignancies:possible involvement of regulatory T cells in disease progression[J].Cancer,2003,98(5):1089-1099.
  • 6Curiel T J,Coukos G,Zou L,et al.Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival[J].Nat Med,2004,10(9):942-949.
  • 7Sakaguehi S,Sakaguehi N,Asano M,et al.Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25).Breakdown of a singlemechanism of seIf-tolerance cause various autoimmune diseases[J].J Immunol,1995,155(3):1151-1164.
  • 8Baecher-Allan C,Anderson D E.Regulatory cells and human cancer[J].Semin Cancer Biol,2006,16(2):98-105.
  • 9Sharma S,Yang S C,Zhu L,et al.Tumor cyclooxygenase2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4^+CD25^+ T regulatory cell activities in lung cancer[J].Cancer Res,2005,65(12):5211-5220.
  • 10Li X,Ye D F,Xie X,et al.Proportion of CD4^+CD25^+ regulatory T cell is increased in the patients with ovarian carcinoma[J].Cancer Invest,2005,23(5):399-403.

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