兰索拉唑口服治疗消化性溃疡急性大出血

Lansoprazole orally in treating peptic ulcer with acute massive bleeding

目的：观察兰索拉唑口服治疗消化性溃疡急性大出血的疗效。方法：３０例消化性溃疡急性大出血病人（男性２４例，女性６例，年龄４８±ｓ１６ａ）予兰索拉唑３０ｍｇ，ｐｏ，ｑｄ×（１０～１４ｄ），并酌情输液、输血。结果：兰索拉唑３０例（１００％）止血成功，住院天数为１４．１±２．１ｄ；输血量为０。未见药物不良反应。结论：兰索拉唑口服对消化性溃疡急性大出血有良好疗效。

AIM: To observe the therapeutic effect of lansoprazole orally to treat peptic ulcer complicated with acute massive bleeding. METHODS: Lansoprazole 30 mg qd po(for 10-14 d) was administrated to 30 patients (M 24, F 6, age 48±16) with peptic ulcer with acute massive bleeding, fluids and blood were transfused in need. RESULTS: Hemostasis was attained in 30 patients (100%) in lasoprazole group. Average days to stay in hospital were 14.1±2.1 d. Average volume of blood transfusion was zero. No adverse reaction appeared. CONCLUSION: Lansoprazole po is very effective in curing peptic ulcer with acute massive bleeding.