老年脂肪肝与动脉粥样硬化的关系

Relationship between fatty liver and artherosclerosis in elders

目的探讨老年脂肪肝与动脉粥样硬化的关系。方法132例年龄>60岁的老年住院患者根据B超检查结果分为2组,脂肪肝组62例和非脂肪肝组70例,对2组患者的动脉粥样硬化情况及其相关因素进行分析。结果脂肪肝组糖尿病患病率、脉压、空腹血糖、甘油三酯及载脂蛋白B均高于非脂肪肝组,高密度脂蛋白低于非脂肪肝组,差别均有统计学意义(P<0.05);脂肪肝组颈动脉斑块检出率和颈动脉内膜中层厚度均高于非脂肪肝组,差别有统计学意义(P<0.05)。结论老年脂肪肝患者动脉粥样硬化的患病率高于非脂肪肝患者,脂肪肝为动脉粥样硬化的危险因素。

Objective To investigate the relationship between fatty liver and atheroselerosis in elders. Methods One hundred and thirty-two elders （ 〉 60 years ） were divided into fatty liver group （n = 62 ） and non-fatty liver group （n = 70 ）. The correlation between atherosclerosis and related factors were studied. Results Compared with non-fatty liver group, prevalence rate of diabetes,pulse pressure, fasting blood glucose, triglyceride, apolipoproteinB were significantly increased （P 〈 0.01, P 〈 0. 05 ）, while high density lipoprotein was significantly decreased （ P 〈 0.01 ）. The common carotid artery intima-media thickness and the rate of carotid artery plaque of fatty liver group were significantly higher than those of non-fatty liver group （P 〈 0.01, P 〈 0.05）. Conclusion The risk of atheroselerosis is higher in elderly patients with fatty liver than the patients without fatty liver. Fatty liver is a risk factor of atheroselerosis.