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EphrinA2是促进肝癌生长转移的相关基因 被引量:1

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摘要 据2009年11月20日Hepatology报道.中国科学院上海生命科学研究院营养科学研究所谢东研究组发现了促进肝癌生长和转移的相关基因“EphrinA2”及其相关分子机制。
出处 《生物医学工程与临床》 CAS 2010年第1期26-26,共1页 Biomedical Engineering and Clinical Medicine
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  • 1Van Geer MA, Brevoord D,Kuhlmann KF, et al. A fiber modified ade-novims vector that targets to the EphrinA2 receptor reveals enhancedgene transfer to ex vivo pancreatic cancer[J]. Int J Oncol, 2010,35(1):233-244.
  • 2Feng YX, Zhao JS, Li JJ, et al. Liver cancer: EphrinA2 promotes tu-morigenicity through Rac 1 /Akt/NF-kappaB signaling pathway 120[J].Hepatology, 2010, 51(2):535-544.
  • 3Bowden TA, Aricescu AR, Nettleship JE, et al. Structural plasticity ofeph receptor A4 facilitates cross-class ephrin signaling [J].Structure,2009,17(10): 1386-1397.
  • 4Irie N, Takada Y, Watanabe Y, et al. Bidirectional signaling throughephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteo-blastogenesis[J]. J Biol Chem. 2009, 2S4< 21): 14637-14644.
  • 5Peuckert C,Wacker E, Rapps J, Levitt P. Aliaptive changes in gene ex-pression patterns in the somatosensory cortex after deletion of ephri-nA5[J]. Bolz J.Mol Cell Neurosci, 2008,39(1):21-31.
  • 6Rapti M, Atkinson SJ, Lee MH, Trim A, Moss M, Murphy G. The iso-lated N-terminal domains of TIMP-1 and TIMP-3 are insufficient forADAM10 inhibition[J]. Biochem J; 2008,411(2):433-439.
  • 7Kojima T, Chung TY, Chang JH, Sayegh R, Casanova FH, Azar DT.Comparison of EphA receptor tyrosine kinases and ephrinA ligandexpression to EphB-ephrinB in vascularized comeas[J]. Cornea, 2007,26(5):569-578.
  • 8Kimura J,Katahira T, Araki I,Nakamura H. Possible role of Hes5 forthe rostrocaudal polarity formation of the tectum [J]. Dev Growth Dif-fer, 2004, 46(3):219-227.
  • 9Fox BP, Kandpal RP. Invasiveness of breast carcinoma cells and tran-script profile: Eph receptors and ephrin ligands as molecular markersof potential diagnostic and prognostic application [J]. Biochem Bio-phys Res Commun, 2004,318(4):882-892.
  • 10Nakamura H, Sugiyama S. Polarity and laminar formation of the op-tic tectum in relation to retinal projection [J]. J Neurobiol, 2004, 59(1):48-56.

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