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烟雾病双源CT与三维全脑灌注血容量成像的初步应用 被引量:14

Preliminary Study of Dual-source CT Angiography and Three-dimensional Whole Brain Perfused Blood Volume Imaging in Patients with Moyamoya Disease
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摘要 目的:评价双源CT血管成像(CTA)联合三维全脑灌注血容量成像(PBV)在烟雾病患者中的应用价值。方法:13例可疑烟雾病病例在3天内行双源CT和DSA检查。在双源CTA上对颅底血管狭窄、烟雾病血管的严重程度进行判定,并与DSA进行对照。在三维全脑PBV上,测量双侧额叶大脑前动脉供血区和大脑中动脉供血区皮层、颞叶皮层、枕叶皮层、基底节区的血容量;并按照DSA评价标准进行比较。结果:在诊断颅底血管狭窄程度上CTA与DSA有9例完全符合,在烟雾病血管严重程度的判断上CTA与DSA有8例判断一致。三维全脑PBV能够显示不均质性的脑血容量降低,侧别和部位上血容量的差异无统计学意义(P>0.05)。结论:双源CTA联合三维全脑PBV技术可用于评价烟雾病患者脑部血管形态和血容量改变。 Objective:To evaluate the clinical value of dual source CT angiography (DS-CTA) in combination with three-dimensional perfused blood volume imaging (3D-PBV) in Moyamoya disease. Methods.. Thirteen patients with suspected Moyamoya disease underwent DS-CTA and digital subtraction angiography (DSA) with 3 days. The degree of vascular stenosis in skull base and the seriousness of Moyamoya vessels visualized on CTA were correlated with that of DSA. The feeding area in bilateral frontal lobes by anterior cerebral arteries and the blood volume of the cortex fed by middle cerebral arteries, cortex of temporal lobe, occipital lobe and basal ganglia were measured; these measurements were compared with DSA according to the DSA classification. Results: The degree of stenosis of blood vessels were in full coincidence in 9 pa- tients with both DS-CTA and DSA. The assessment and the evaluation of seriousness of Moyamoya vessels was in coincidende in 8 patients. Inhomogeneous decrease of blood volume of brain could be revealed on 3D-PBV imaging;however,there was no statistical difference for the laterality and location in the measurements. Conclusion: DS-CTA in combination with 3D-PBV could be used in the evaluation of the morphology of cerebral blood vessels as well as the changes of blood volum in Moyamoya disease.
出处 《放射学实践》 北大核心 2010年第1期19-23,共5页 Radiologic Practice
关键词 脑底异常血管网病 血管造影术 数字减影 体层摄影术 X线计算机 Moyamoya disease Angiography,digital subtraction Tomography, X-ray computed
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