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雌激素系统与非小细胞肺癌的相关研究进展 被引量:12

Recent advances in association studies of estrogen system and non-small cell lung cancer
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摘要 肺癌是目前死亡率最高的恶性肿瘤,严重威胁着人们的健康和生命,其中80%为非小细胞肺癌(non-small cell lungcancer,NSCLC)。近年来的研究发现,雌激素系统与NSCLC的生物学行为存在着密切联系。同时,患者体内的雌激素水平亦可对其病情及预后产生影响。因此,针对雌激素的治疗已成为目前NSCLC诊治的一大热点。本文就雌激素系统在NSCLC治疗领域的相关研究进展进行综述。 Lung cancer,a malignant cancer with highest death rate,severely threats the people's health.80% lung carcinomas are non-small cell lung cancer(NSCLC).Recent studies have found that estrogen system has close relationship with the biological behaviors of NSCLC.Meanwhile,the level of estrogen influences the progression of disease and the prognosis of lung cancer patients.As a result,estrogen pathway has become a hot target in NSCLC treatment.This paper reviews the recearch advances of estrogen system in NSCLC treatment.
出处 《肿瘤》 CAS CSCD 北大核心 2010年第1期77-80,共4页 Tumor
关键词 非小细胞肺 雌激素类 受体 雌激素 预后 Carcinoma non-small cell lung Estrogens Receptors estrogen Prognosis
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  • 1吴秉铨.癌的分子标志物及其临床意义[J].中华病理学杂志,1997,26(1):4-5. 被引量:9
  • 2宋永平,房佰俊,魏旭东,郑树.K562/Vp16细胞系中边缘细胞对伊马替尼耐药机制的初步研究[J].中华血液学杂志,2005,26(11):669-673. 被引量:4
  • 3Fairlamb D,Boesen E. Gynaecomastia associated with gonadotrophin-secreting carcinoma of the lung [J]. Postgrad Med J, 1977,53(7):269-271.
  • 4刘国龙,盛信秀.性激素与肿瘤[M].见:性激素与老年疾病.吴赛珠.第1版.北京:中国科学技术出版社,1997:199-211.
  • 5Lu Q,Nakmura J,Savinov A,et al. Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers [J]. Endocrinology,1996,137(7):3061-3068.
  • 6Thijssen JH,Daroszewski J,Milewicz A,et al. Local aromatase activity in human breast tissues [J]. J Steroid Biochem Mol Biol,1993,44:577-582.
  • 7Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small cell lung cancer. New Engl J Med,2002,346: 92-98.
  • 8Lara Jr PN, Gandara DR, Longmate J, et al. Activity of high-dose toremifene plus cisplatin in platinum-treated non-small-ell lung cancer: a phase Ⅱ California Cancer Consortium Trial. Cancer Chemother Pharacol,2001,48: 22-28.
  • 9Pu YS, Hsieh TS, Tsai TC, et al. Tamoxifen enhances the chemosensitivity of bladder carcinoma cells. J Urol, 1995,154: 601-605.
  • 10Fabian C, Sternson L, EI-Serafi M, et al. Clinical pharmacology of tamoxifen in patients with breast cancer : correlation with clinical data. Cancer,1981,48: 876-882.

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