应用^(60)Co-γ射线辐照保存川产道地中药材的研究

Protecting the native Sichuan crude drugs from mildewing and motheating by ^(60) Coγ- ray radiation

目的：研究运用６０Ｃｏγ射线辐照保存川产道地中药材。方法：选用７种有代表性的川产道地中药材，通过辐照剂量的筛选，对中药材在不同剂量６０Ｃｏγ射线辐照后的霉变和虫蛀、细菌生长活力，感观形态及组织形态学，有效成分的定性、定量分析，以及毒副作用进行观察。结果：经８０００Ｇｙ辐照后的中药材主要有效成分、组织形态和感观性态不变，能有效地防止霉变和虫蛀，无毒副作用且卫生安全。

OBJECTIVE: To study protecting the native Sichuan crude drugs from mildewing and motheating by^(60) Coγ-ray radiation. METHOD: Seven native Sichuan crude drugs were selected as samples, to optimise the radiation dose. After the samples were radiated, we observed the effects of radiation on protecting the medicines from mildewing and motheating, determined the growthrate of mould, and studied the changes in morphology, toxicity and main active fractions. RESULTS: Compared with the controls, the morphology toxcity and main active fractions of the samples showed no changes after having been radiated with 8 000 Gy, which is the most effective dose for protecting the samples from mildewing and motheating. CONCLUSION: It is an economical, safe and effective way to protect the native Sichuan crude drugs from mildewing and motheating by ^(60) Coγ- ray radiation.