期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Association between intervertebral disc degeneration and disturbances of blood supply to the vertebrae 被引量：3

Association between intervertebral disc degeneration and disturbances of blood supply to the vertebrae
原文传递
导出
摘要 Low back pain is a common public health problem in western industrialized societies and the world as well.Studies indicate that the prevalence rate ranges to 35%, with around 10% of patients from 12% becoming chronically disabled. It also places an enormous economic burden on society. Although the exact cause of low back pain has yet to be defined, intervertebral disc degeneration is considered a major source of it. Since patients with degenerative discs are often asymptomatic, the mechanisms of it are still unclear. Low back pain is a common public health problem in western industrialized societies and the world as well.Studies indicate that the prevalence rate ranges to 35%, with around 10% of patients from 12% becoming chronically disabled. It also places an enormous economic burden on society. Although the exact cause of low back pain has yet to be defined, intervertebral disc degeneration is considered a major source of it. Since patients with degenerative discs are often asymptomatic, the mechanisms of it are still unclear.
作者 TIAN Wei QI Hui
机构地区 Department of Spinal Surgery. Beijing Jishuitan Hospital Institute of Traumatology and Orthopaedics
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2010年第2期239-243,共5页 中华医学杂志（英文版）
关键词 intervertebral disc DEGENERATION low back pain NUTRIENT atherosclerosis SMOKING NICOTINE intervertebral disc degeneration low back pain nutrient atherosclerosis smoking nicotine
分类号 S858.292 [农业科学—临床兽医学] S852.33 [农业科学—基础兽医学]
  • 相关文献

参考文献49

  • 1Mauiadakis N, Gray A. The economic burden of back pain in the UK. Pain 2000; 84: 95-103.
  • 2Hadjipavlou AG, Tzermiadianos MN, Bogduk N, Zindrick MR The pathophysiology of disc degeneration: a critical review. J Bone Joint Surg Br 2008; 90: 1261-1270.
  • 3Colombini A, Lombardi G, Corsi MM, Banff G.Pathophysiology of the human intervertebral disc. lnt J Biochem Cell Biol 2008; 40: 837-842.
  • 4Humzah MD, Soames RW. Human intervertebral disc: structure and function. Anat Rec 1988; 220: 337-356.
  • 5Lundon K, Bolton K. Struclure and function of the lumbar intervertebral disk in health, aging, and pathologic conditions. J Orthop Sports Phys Ther 2001.31 : 291-303.
  • 6Chelberg MK, Banks GM, Geiger DF, Oegema TR Jr. Identification of heterogeneous ceil populations in normal human intervertebrat disc. J Anat 1995: 186: 43-53.
  • 7Roberts S, Evans H, Trivedi J, Menage J. Histology and pathology of the human intervertebral disc. J Bone Joint Surg Am 2006; 88 (Suppl 2): S10-S14.
  • 8Guiot BH, Fessler RG. Molecular biology, of degenerative disc disease. Neurosurgery 2000; 47: 1034-1040.
  • 9Urban JR Roberts S. Degeneration of the intervertebral disc. Arthritis Res Ther 2003; 5: 120-130.
  • 10Higuchi M, Kaneda K, Abe KU. Postnatal histogenesis of the cartilage plate of the spinal column: clectron microscopic observation. Spine 1982; 7: 89-96.

同被引文献52

  • 1Schizas C, Kulik G, et al. Disc degeneration : current surgi- cal options[J]. Eur Cell Mater,2010,43(20) :306-315.
  • 2Le Maitre CL, Hoyland JA, Freemont AJ. Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate hu- man intervertebral disc: an in situ zymographic and gene therapy study [J]. Arthritis Res Ther,2007,9(4) :R83.
  • 3Kim JS,Ellman MB. Insulin-like growth factor 1 synergi- zes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells [J]. Arthritis Rheum,2010,62(12) :3706-3715.
  • 4Miyazaki M, Sugiyama O, Tow B, et al. The effects of lentiviral gene therapy with bone morphogenetic protein - 2-producing bone marrow cells on spinal fusion in rats [J]. J Spinal Disord Teeh,2008,21(5) :372-379.
  • 5LevicofI EA,Kim JS, Sobajima S, et al. Safety assessment of intradiscal gene therapy Ⅱ [J]. Spine, 2008,33(14): 1509-1516.
  • 6Nomura T, Mochida J, Okuma M, et al. Nucleus pulposus allograft retards intervertebral disc degeneration [J]. Clin Orthop, 2001 ; 34 ( 389 ) : 94-101.
  • 7Iwashina T, Mochida J ,Sakai D. Feasibility of using a hu man nucleus pulposus cell line as a cell source in cell transplantation therapy for intervertebral disc degenera- tion [J ]. Biomaterials, 2006,31 ( 11 ) : 1177-1186.
  • 8Yang F,Leung VY,Luk KD. Mesenchymal stem cells ar- rest intervertebral disc degeneration through chondrocyte di{ferentiation and stimulation of endogenous cells[J].Spine,2009,17(ll):1959-1966.
  • 9Gaetani P, Torre ML, Klinger M. Adipose-derived stem cell therapy for intervertebral disc regeneration: an in vitro recon- structed tissue in alginate capsules [J]. Tissue Eng, 2008,14 (8) : 1415-1423.
  • 10Vierhuchen T, Ostermeier A, Pang ZP, et al. Direct con- version of fibroblasts to functional neurons by defined factors [J]. Nature,2010,463(7284) :1035-1041.

引证文献3

二级引证文献35

Chinese Medical Journal
2010年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部