多囊卵巢综合征临床特征分析

THE ANALYSIS OF CLINICAL CHARACTER OF WOMEN WITH POLYCYSTIC OVARY SYNDROME

目的:分析内蒙古地区多囊卵巢综合征临床表现特点。方法:回顾性分析110例PCOS临床特征及内分泌、血糖、血脂、胰岛素等检查指标。结果:110例PCOS病人中月经稀发102例,闭经8例。肥胖66例(腹型肥胖为主),瘦弱3例。高血甘油三酯29例,高血γ-谷氨酸转氨酶26例。临床高雄激素表现49.1%,生化高雄激素20%。以胰岛素抵抗指数HOMA-IR≥1.66判为IR的有14例占12.7%(空腹胰岛素均≥23μU/ml),均为胖型体质。流产后月经稀发出现PCOS临床特征的有21.8%(24/110)。结论:PCOS病人肥胖发生率较高,肥胖型PCOS病人较非肥胖型存在更严重的内分泌及代谢紊乱,胖型体质的PCOS病人高雄激素及胰岛素抵抗的发生率均高,瘦型体质的PCOS病人以高雄激素发生率高,但胰岛素抵抗发生率低,早孕流产可以诱发PCOS的发病。

Objective： To analysis the clinical date of women with PCOS in inner mongolian. Methods：110 cases of patients with PCOS had Clinical presentations of serum hormonal levels, glucose levels, insulin levels and lipid in netnospe coive study. Results： The presence of oligomenorrhea was 92.7% ,while amenorrhea was 7.3%. There were 66 obesity cases （ of which 65 patients were cen- tral obesity） and 3 thin cases. Hypertriglyceridemia 29 had been found in cases, high level of ~/- ami- nobutyric acid transaminase （ GABA - T） had been found in 26 cases. The percentage ment of clinical manifestation of hyperandrogenism was 49. 1%, and biochemical hyperandrogenism was 20%. The presence of insulin resistancel4 （ 12.7% ） cases （ HOMA - IR ≥1.66）, meanwhile FINS ≥23 μU/mL, manifestation of oligo - ovulation after abortion was 21.8% （24/110）. Conclusion： The prevalence rate of obesity is higher in PCOS. The state of obesity has a positive relation with disorder of endocrine and insulin resistance, in thin group of PCOS, clinical and/or biochemical signs of hyperandrogenism are higher than insulin resistance, abortion can induce clinical manifestations of oligo - ovulation in PCOS.