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新生儿感染性肺炎与血清IL-6、IL-8活性关系的探讨 被引量:3

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摘要 新生儿感染性肺炎的发病与机体的免疫状况有关,为探讨其与IL-6,IL-8的关系及临床意义,本组应用ELISA法检测45例患儿,其中重症肺炎12例,普通肺炎33例,正常对照新生儿28例,结果显示患儿组IL-6、IL-8水平显著高于对照组(P<0.01)。患儿组中重症组及CRP阳性组的IL-6值又高于普通组和CRP阴性组;IL-8在血培养阳性组中高于阴性组。经治疗普通肺炎、CRP阴性,血培养阴性组的IL-6恢复正常更快,提示IL-6、IL-8参与新生儿感染性肺炎的发病过程,IL-6与病情和预后关系更为密切。
出处 《临床儿科杂志》 CAS CSCD 北大核心 1998年第4期263-264,共2页 Journal of Clinical Pediatrics
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