言语诱发听性脑干反应的稳定性研究

Research on the Stability of Speech-evoked Auditory Brainstem Response

目的:研究正常青年人的言语诱发听性脑干反应(speech-ABR)在不同时间段下的测试结果,为speech-ABR的稳定性研究提供实验依据,促进speech-ABR在基础及临床研究中的应用。方法:选取40名健康青年并随机分为两组进行speech-ABR测试,两组测试时间相隔2个月。比较两组反应主波的潜伏期及幅值,分析反应主波的引出率。结果:两组测试人群均很好引出speech-ABR,两组反应各主波的潜伏期及幅值差异无统计意义。反应主波以V、A、C和F波的引出率较高。结论:speech-ABR的测试结果具有较好的稳定性,其V、A、C和F波可作为临床观测的重要指标,是言语感知机制的基础及临床研究的良好工具。

Objective： To investigate the speech-evoked brainstem response （speech-ABR） of normal young people under different recording periods, which can provide the experimental evidences for researches on the stability of speech-ABR and promote its applications in clinical researches. Methods： 40 healthy young people were randomly divided into two groups, which were tested following the same protocol at different time of two months interval. Latencies and amplitudes of the feature peaks in these groups were compared and the rates of appearance （detection rate） of the feature peaks were analyzed statistically. Results： Speech-ABRs were recorded successfully in two groups. The latencies and amplitudes of feature peaks in these groups were not different statistically, and the detection rates of V, A, C and F peaks were higher than others. Conclusion： The speech-ABRs of the two groups are stable, and the V, A, C and F peaks can be used as important indicators of clinical observation, showing that Speech-ABR is a promising tool in the study of Speech perception mechanism.