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多沙唑嗪在输尿管远段结石体外震波碎石术后的应用

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摘要 目的评估多沙唑嗪在输尿管远段结石体外震波碎石(ESWL)后应用的效果。方法把131例输尿管下段结石患者随机分成对照组和治疗组。对照组ESWL后抗炎治疗3d,每天服用排石冲剂,饮水不少于1.5L;治疗组在对照组治疗方案基础上予以口服1受体阻滞剂多沙唑嗪4mg,1次/d。观察结石排出情况、出现绞痛时镇痛药的使用次数和药物的不良反应。每例患者观察时间不超过4周。结果对照组排石完全排出42例(66.7%),治疗组排石完全排出41例(82.4%),两组比较差异具有显著性(<0.05)。对照组平均使用止痛药次数1.08次,而治疗期间治疗组平均使用止痛药次数0.62次,两组比较差异具有显著性(<0.01)。治疗组除2例发生眩晕外,无其他不良反应发生,而对照组无不良反应发生。结论多沙唑嗪能提高输尿管下段结石ESWL后的排石率,减少止痛药的使用次数,且安全有效,可作为输尿管下段结石ESWL后的辅助排石方法。
出处 《现代实用医学》 2009年第12期1343-1343,1345,共2页 Modern Practical Medicine
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