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上皮样血管平滑肌脂肪瘤6例临床病理分析 被引量：3

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摘要 目的探讨上皮样血管平滑肌脂肪瘤(epithelioid angiomyolipoma,EAML)的临床病理特点、免疫表型,诊断及鉴别诊断。方法对5例肾脏和1例肝脏上皮样血管平滑肌脂肪瘤进行病理形态观察及免疫组织化学检测。结果6例上皮样血管平滑肌脂肪瘤形态相似,肿瘤细胞多呈巢状和片状排列,围绕血管呈袖套状,瘤细胞体积大,形态单一,多边形或梭形,胞质丰富,嗜酸性颗粒状,细胞核较大,核仁明显呈空泡状。免疫组化显示肿瘤细胞HMB45、vimentin和平滑肌特异性抗原(SMA,MSA)弥漫阳性;而EMA、CK(AE1/AE3)呈阴性。结论上皮样血管平滑肌脂肪瘤是一种具有恶性潜能的间叶源性肿瘤,形态学上常容易误诊,免疫组化对鉴别诊断有重要意义。
作者 张海燕 刘安丽
机构地区 河南省南阳医学高等专科学校附属医院病理科
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2009年第6期637-639,共3页 Chinese Journal of Clinical and Experimental Pathology
关键词 上皮样血管平滑肌脂肪瘤 免疫组织化学 诊断 鉴别诊断
分类号 R730.262 [医药卫生—肿瘤]
  • 相关文献

参考文献9

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二级参考文献11

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共引文献9

同被引文献25

  • 1王占东,王小玲.血管周上皮样细胞分化肿瘤的研究进展[J].临床与实验病理学杂志,2005,21(1):115-116. 被引量：10
  • 2蒋力明,赵心明,王爽,欧阳汉,张宏图,周纯武.肝脏血管平滑肌脂肪瘤的CT、MR表现与手术病理对照研究[J].中国肿瘤临床,2005,32(17):1004-1007. 被引量：15
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引证文献3

二级引证文献6

临床与实验病理学杂志
2009年 第6期

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