摘要
目的：建立汝安膜中盐酸小檗碱的含量测定方法。方法：使用C18柱,0.03 mol/L磷酸二氢钠溶液-乙腈（68∶32）为流动相,检测波长为348 nm。结果：盐酸小檗碱在0.4-2.0 mg/L范围内线性关系良好,平均回收率为98.04%（n=6）,RSD为0.89%。结论：该方法准确、可靠、重现性好,可作为该膜剂的质量控制方法。
Objective： To establish the method of detecting berberine hydrochloride contents of.Methods： HPLC was used to determine berberine hydrochloride in RU AN membrane on C18 column,using 0.03 mol/L NaH2PO4-CH3CN（68∶32） as mobile phase,with detection at 348 nm.Results： The good linearity was observed for the concentration of 0.4-2.0 mg/L.The average recoveries were 98.04%（n = 6）.RSD were 0.89%.Conclusion： It is accurate,safe,good in reappearing rate,and can be used as the quality control method for the membrane medication.
出处
《河南大学学报（医学版）》
CAS
2009年第4期281-283,共3页
Journal of Henan University:Medical Science
基金
开封市科技攻关项目(030003)
