胃食管反流病患者年龄分层及中医证型研究

Study on Age Stratification and TCM Patterns of Gastroesophageal Reflux Disease

目的:观察胃食管反流病患者人群年龄分层的临床特征及中医证型分布特点。方法:通过流行病学现场调查,收集胃食管反流病患者的临床资料,比较年龄≥60岁的老年人群组与年龄<60岁的中青年人群组在食管炎症程度、临床症状、中医证型及生活质量方面的差异。结果:老年人群泛酸症状的发生频率低于中青年人群(P<0.05);脘痞胀症状的发生频率高于中青年人群(P<0.05)。老年人群中虚气逆证的比例高于中青年人群(P<0.05)。老年人群在活力、生理功能、疼痛、总体健康4个维度的生活质量评分明显低于中青年人群(P<0.05)。结论:胃食管反流病老年患者人群具有不同于中青年患者群的特点,应当采取有针对性的治疗。

Objective： To investigate the clinical characteristics and distribution law of TCM patterns in patients with gastroesophsgeal reflux disease（GERD） of different age stratum. Methods： The clinical data of patients with GERD were collected by epidemiologic spot investigation. The patients were divided into elderly aged group （age ≥60） and young and middle-aged group （age 〈 60）. The comparison of grade of esophagitis, clinical symptoms, TCM patterns and quality of life were made between the two groups. Results ：The incidence of acid reguritation symptom of elderly aged group was significantly lower than that of young and middie-aged group ; while, the incidence of gastrectasia symptom of the former was higher than that of the latter （ P 〈 0.05 ）. The proportion uf spleen-hypofunction and qi-reversing pattern of the tormer was higher than that of the latter. The scores of life quality of elderly aged group were significantly lower than of young and middle-aged group in the four dimensions of vitality, physical function, pain and general health（ P 〈 0.05 ）. Conclusions： Elderly patients with GERD have their unique clinical characteristics and should be treated with pertinent measures.