高原藏族酒精性肝病的病理分析

PATHOLOGICAL CHANGES OF LIVER IN ALCOHOLIC LIVER DISEASE IN TIBETER LIVING AT HIGH ALTITUDE

目的与方法：本文对１５０例酒精性肝病、２１０例慢性乙型肝炎的肝穿标本的病理变化进行了比较；结果：在酒精性肝病中常见肝细胞的脂变、小叶肝细胞和窦周纤维化以及中性白细胞浸润，在乙型肝炎中均少见。而乙型肝炎中常见的是汇管区及其周围炎、碎屑状坏死和桥接坏死以及淋巴细胞浸润，在酒精性肝病少见，且程度轻。

Objective:To observate the pathological changes of liver in Tibeter with alcoholic liver disease,living at high altitude.Methods:Samples of tissue of liver were collected by biopsy in 150 patients with alcoholic liver disease and 210 cases with chronic hepatitis B,and the pathological test was performed and compared in both groups.Results:In these samples,we found that there were more fatty degeneration,small liver cell,perisinusodal fibrosis and inflammation in alcoholic liver disease than in chronic hepatits B.In contrast,more inflammation in portal areas and its surroundings,piecemeal and bridging necrosis in chronic hepatitis B.Conclusion:It is important to identify the alcoholic liver disease and chronic hepatitis B in Tibeter living at high altitude with our mthod in this report.