摘要
以4-氯甲基-4'-正烷基-1,1-双环己烷与3,4,5-三氟苯腈为原料,通过格氏反应合成中间体酮,再经黄鸣龙还原得多氟乙烷类液晶化合物,总收率≥60%。
A series of SFM thane-type liquid crystals were synthesized from 4 -chloromethyl-4′ -alkyl-bicyclohexyl and 3, 4, 5-Trifluorobenzonitrile as the raw materials. They were synthesized to intermediate ketone following Grignard reaction pathway. And then the ketone was reduced in the fashion of Wolff-Kishner-Huang-Minlon reduction to gain the final product. The total yield is higher than 60%.
出处
《河北化工》
2010年第2期5-6,23,共3页
Hebei Chemical Industry
关键词
多氟乙烷类
液晶
格氏反应
黄鸣龙还原
合成
SFM ethane-type
liquid crystals
grignard reaction
wolff-kishner-huang-minlon reduction
synthesis
