脂肪因子与餐后高血糖的研究进展

Progress of Researches on Adipocytokines and Postprandial Hyperglycaemia

近年研究发现,脂肪组织是具有内分泌功能的器官。它分泌瘦素、脂联素、肿瘤坏死因子-α、抵抗素、内脂素等脂肪因子。这些细胞因子可能通过参与炎性反应与物质能量的代谢过程,影响胰岛素的生物学效应,影响餐后血糖水平。本文就近年来一些较多关注的脂肪因子与餐后高血糖关系作一综述,为临床控制餐后高血糖,从而降低心血管事件、预防代谢综合征提供依据。

Recent researches have shown that white adipose tissue is a large endocrine organ, which can excrete various of cell factors including adiponectin, leptin, TNF-α, resitin and so on. These cell factors may influence the biological effect of insulin and postprandial glucose by participating in inflammation and affecting energy metabolism. We summarize the relation of adipoeytokines and postprandial hyperglycaemia on purpose of providing more evidence of decreasing cardiovascular events and preventing metabolic syndrome by control of postprandial hyperglycaemia.