阻塞性睡眠呼吸暂停低通气综合症与高血压的相关研究

Related Reseach between OSAHS and Hypertenson

目的 分析伴有高血压的阻塞性睡眠呼吸暂停低通气综合症（oSAHS）的睡眠呼吸障碍特点，并探讨两者之间的关系。方法 对诊断为OSAHS患者中45例高血压和32倒非高血压患者进行基础情况和夜间缺氧程度、睡眠结构和干扰睡眠因素以及OSAHS患者中高血压的危险因素进行分析。结果 高血压组睡眠呼吸暂停低通气指数（AHI）高于非高血压痛组．体重指数（BMI）是引起两组间睡眠呼吸暂停低通气指数（AHI）差异的显著因素。两组间夜间平均Sa02和最低Sa02比较差异无显著性（p〈0．05），睡眠呼吸暂停低通气指数（AHI）是引起夜间缺氧的显著因素。OSAHS患者中高血压病的危险因素是AHI、年龄、BMI。结论 OSAHS伴有高血压的患者的睡眠呼吸障碍程度更重，而夜间低氧血症与高血压无关,但与睡眠呼吸障碍的严重程度有关。年龄、肥胖和睡眠呼吸障碍的严重程度是OSAHS患者中高血压的危险因素。

Objective To analyze the hypertension associated with obstructive sleep apnea-hypopnea syndrome （OSAHS） characteristics of sleepdisordered breathing and to explore the relationship between the two. Methods Analysis for diagnosis of OSAHS patients, 45 patients with hypertension and 32 cases of non-hypertensive patients with base case and night oxygen levels, sleep structure and sleep disturbance factors as well as in patients with OSAHS of risk factors for hypertension~ Results Hypertension sleep apnea-hypopnea index （AHI） higher than non-patients with hypertension, body mass index （BMI） between the two groups is a cause of sleep apnea-hypopnea index （AHI） significant differences in the factors. At night between the two groups the average difference between SaO2 and lowest SaO2 was no significant （p 〈0.05）, sleep apnea-hypopnea index （AHI） is caused by a significant factor in hypoxia at night. OSAHS patients with hypertension risk factors AHI, age, BMI.Conclusion OSAHS patients with hypertension associated with sleep-disordered breathing have heavier levels, while the nocturnal hypoxemia and hypertension, but with the sleepdisordered breathing severity. Age, obesity and sleep-disordered breathing in patients with OSAHS severity of hypertension risk factors.