摘要
目的 观察IZL-2003免疫治疗系统对化疗患者骨髓抑制的近期疗效和生存质量的影响。方法 40例晚期胰腺癌患者随机分为对照组(化疗后给予维生素C、维生素B6),治疗组(化疗后给予免疫治疗),各20例,治疗10d为1个疗程。结果 治疗组外周血白细胞数明显增多,与对照组比较,差异有显著性(p〈0.05);治疗组KPS改善优于对照组(p〈O.05)。生存质量治疗组优于对照组(P〈0.05)。结论 IZL-2003免疫治疗系统能拮抗化疗所致白细胞减少,并在一定程度上改善患者KPS评分,提高生存质量。
Objective To observe the'recently therapeutic effects of IZ L2 2003 immune therapy system on myelosuppression induced by chemotherapy and its effect on life quality in advanced pancreatic cancer patients. Methods Forty cases of advanced pancreatic cancer patients were randomly into two groups. Treat ment group(n=20) was given IZL-2003 immune therapy system after chemotherapy,and control group was given vitamin C and vitamin B6 after chemotherapy, for 10 d as a course. Results There was difference between two groups on the increasing rate of white blood cell (p〈O.05); There was significant difference between treat ment group and control group on KPS scale increasing rate (p〈0.05). The life quality of the treatment group is better than that of the control group (p〈0.05). Conclusion IZL-2003 immune therapy system can antagonize myelosuppression induced by chemotherapy, and improve KPS and life quality in advanced pancreatic cancer patients
作者
靳彩玲
刘晶
王巧珍
路平
JIN Cai-ling, LIU-Jing,WANG Qiao-zhen,LU-Ping (Department of MedicalOncology,the First Affiliated Hospital of Xinxiang Medical College,Weihui 453100,China)
出处
《医学信息》
2010年第2期407-408,共2页
Journal of Medical Information