Significance of Laboratory and Clinical Manifestations of Antiphospholipid Syndrome

Clinical features of antiphospholipid syndrome Antiphospholipid syndrome(APS) is a form of immune mediated thrombophilia,characterized by thrombosis, recurrent fetal death and the presence of circulating antiphospholipid(aPL) antibodies directed against anionic phospholipids or protein-phospholipid complexes. Almost every vascular bed can be involved by

Clinical features of antiphospholipid syndrome Antiphospholipid syndrome （APS） is a form of im- mune mediated thrombophilia, characterized by thrombo- sis, recurrent fetal death and the presence of circulating antiphospholipid （aPL） antibodies directed against an- ionic phospholipids or protein -phospholipid complexes. Almost every vascular bed can be involved by thrombosis in APS. The most common site for venous thrombosis is the deep venous system of the lower limb. Other sites in- clude the retinal, renal and hepatic vein, thrombosis of the last causing Budd Chiari syndrome.