超临界CO_2萃取和水蒸气蒸馏法萃取沙枣花挥发油工艺的比较研究

Comparative Study of Volatile Oil Extraction Process from Flowers of Elaeagnus angustifolia L.with Steam Distillation and Supercritical CO_2 Extraction

目的比较水蒸气蒸馏法和超临界CO2萃取技术从沙枣花中提取挥发油的得率,确定最佳提取工艺。方法采用正交试验,以挥发油得率为指标,比较超临界CO2萃取及水蒸气蒸馏两种方法的提取效果。结果水蒸气蒸馏法中药材蒸馏时间对提取挥发油的影响最大;而超临界CO2萃取的最佳条件为萃取压力20MPa,萃取温度40℃,CO2流量为10L/h。结论与水蒸气蒸馏法相比,超临界CO2萃取法具有耗时少、效率高和对提取后物料破坏较小等优点,适合于批量生产,便于制剂的后续提取工艺制备。

Objective To optimize the extraction process by determing the volatile oil yield of steam distillation and supercritical CO2 extraction from flowers of Elaeagnus angustifolia L.. Methods Orthogonal test was carried out to compare two extraction effects between steam distillation and supercritical CO2 extraction by detecting the extraction ratio from flowers of Elaeagnus angustifolia L.. Results Steam distillation time on volatile oil extraction has the greatest impaction, and the best condition of supercritical CO2 extraction was extraction pressure of 20 MPa, extraction temperature of 40 ℃, and flux of CO2 is 10 L/h. Conclusion Compared with steam distillation, supercritical CO2 extraction spends less time, has higher efficiency and less harm to the materiel after extracting. It adapts to batch process and is convenient for subsequent extraction technology.