精神分裂症的红细胞和血清含铁量的测定结果及分析

Iron measurement in serum and erythrocyte from schizophrenic patients

目的为了解精神分裂症患者红细胞内外铁含量的变化。方法对５３例精神分裂症患者及５０例正常对照者测定红细胞及血清铁水平进行对照。结果红细胞及血清铁水平均较对照组增高（Ｐ＜０．０１）；病程≥３年患者较＜３年者红细胞铁呈增高趋势，而血清铁则呈下降趋势；红细胞及血清铁水平间无相关性（Ｐ＞０．０５）。结论本实验提示精神分裂症患者体内存在着铁代谢异常。

Objective In order to explore the changes of iron in serum and erythrocyte from schizophrenic patients.Method The distribution of iron in erythrocyte and serum of 53 schizophrenic patiens were compared with that of 50 volunteers matched controls.Results Iron in the erythrocyte and serum were higher in schizophrenic patients than in control group(P<0.01).There were no definite correlation between erythrocyte iron and serum iron(P>0.05).Conclusion The results of study suggest that there are abnormality of iron metabolism in schizophrenic patients.The clinical significances were speculated and discussed preliminarily.