摘要
目的：观察通过纤维胃镜和口服给药两个途径治疗消化性溃疡的疗效。方法：将４６例消化性溃疡患者随机分为对照组２１例和治疗组２５例。２组患者均给予雷尼替丁、硫糖铝和呋喃唑酮口服，治疗组加内镜下用双氧水和中药锡类散、白芨粉的混悬液交替喷洒、涂布溃疡灶。比较２组临床疗效及内镜复查结果。结果：治疗组２５例患者溃疡灶均达到瘢痕期或愈合期，无一例活动期；平均治愈时间为１５．８日；幽门螺旋杆菌（ＨＰ）阴转率为８４．０％。对照组患者溃疡灶活动期３例；平均治愈时间３１．２日；ＨＰ阴转率８０．９％。２组平均治愈时间及ＨＰ阴转率均有显著性差异（Ｐ均＜０．０１）。内镜复查结果，治疗组溃疡复发率亦明显低于对照组（４．５％和２５．０％）。结论：内镜下合用中西药物治疗消化性溃疡疗效高、疗程短、复发率低。
Objective:To observe the therapeutic efficacy of under gastrofiberscope and oral drug on gastric ulcer.Methods:Fortysix cases of gastric ulcer were divided randomly into control group ( 21 cases ) and treatment group (25 cases),they were given ranitidin,aluminum hydroxide and furazolidon.In addition,the treatment group was treated with liquor hydrogen peroxide (H 2O 2) and emulsion consisted of Xilei Powder (锡类散) and bletilla striate powder (traditional Chinese drug) to sprinkl alternately and spread on ulcer lesions under gastroscope.Then,to compare the clinical efficacy and reexamination with gastroscope between 2 groups.Results:In treatment group,25 cases were reached scar stage or healing stage and no case was presented active state;the mean cured time was 15 8 days and the rate of helibacter pylorus (HP) transforming negative was 84 0%;in control group,the ulcerative lesions in 3 cases were activated,the mean cured time was 31 2 days,HP transforming negative rate was 80 9%.There were obvious differences of mean cured time and HP eradicating rate between 2 groups (all P <0 01);additionally,the recurrence rate was 4 5% in treatment group,it was lower obviously than that in control group (25 0%).Conclusions:There are better therapeutic efficacy,short therapy course,lower recurrence rate and no sideeffect of TCM WM treating gastric ulcer under gastroscope.
