鱼腥草注射液静脉给药不良反应分析

Analysis of Houttuynia intravenous injection adverse reactions

目的探讨鱼腥草注射液静脉给药所致的不良反应的临床特点,为临床安全用药提供参考。方法对47例应用鱼腥草注射液致不良反应患者的临床资料进行分析。结果鱼腥草注射液不良反应的发生与年龄、性别无关。静脉注射鱼腥草液体3～10min后出现不良反应7例,10～30min后13例,24h后14例,48h后13例。鱼腥草注射液不良反应可累及多系统多部位的损伤,以皮肤、消化、呼吸、心血管、神经系统多见,严重者可发生过敏性休克反应。结论临床应用鱼腥草注射液时应提高警惕,密切观察,详细询问过敏史,初次注射者应观察15min,严格掌握适应证,避免联合用药。一旦发生过敏反应,应迅速采取相应抢救措施,避免发生严重不良后果。

Objective To discuss clinical feature of Houttuynia cordata injection adverse reaction, to provide reference for clinical safety of drugs. Methods Adverse reactions clinical data of 47 cases patients used Houttuynia cordata injection were analyzed. Results Houttuynia eordata injection adverse reaction had no related in age, sex. After intravenous injection of the liquid of Houttuynia 3 - 10min,7 cases occurred adverse reactions, after 10 - 30min 13 cases, after 24h 14 cases, after 48h 13 cases. Houttuynia cordata injection adverse reactions can affect many parts of the multi-system damage to the skin, digestive, respiratory, cardiovascular, nervous system. Severe anaphylactic shock reactions may occur. Conclusion Clinical application of Houttuynia injection should be vigilant,close observation, ask about the history of allergy in detail. The initial injection patients should be observe 15min, strictly controll indications, avoid the combination therapy. Once adverse reactions occurred,emergency measures should be took to avoid serious adverse effect.