老年高血压病患者经不同方法治疗后的血液流变学指标变化

Hemorheological Index Changes in Elderly Hypertension with Different therapy

目的:探讨老年高血压病患者经不同方法治疗前后血液流变性的变化。方法:检测150例老年高血压病患者及30例健康对照组血液流变学指标,比较两组人群上述指标的差异及高血压病患者经不同方法治疗前后的血液流变学参数的统计学分析结果。结果:高血压病组除红细胞变形系数明显低于健康组外,其它指标均明显高于健康组。老年高血压病组经使用降粘药物和方法后,红细胞变形指数升高,血液粘稠度和红细胞聚集性下降。结论:老年高血压病患者血液呈高粘状态;降粘药物和方法对其有明显改善作用。

Objective:To explore the association between elderly hypertension and hemorheology,and the hemorheological changes before and after different treatments.Method:To measure hemorheological indexes in 150 elderly patients with hypertension(EPH)and 30 health subjects as control group(HC),the parameters of abnormalities and of EPH untreated and treated were analyzed.Results:Hemorrheological parameters of the EPH-group were obviously higher than those of the HC-group.The deformation index of erythrocyte in EPH-group were obviously higher than the HC-group,viscosity and erythrocyte aggregation were lower.The effect of pharmaceutical therapy which can improve the hemorheological condition in EPH-group was remarkable.The deformation index of erythrocyte were increased,the viscosity were decreased.There was no significant difference in all treatment group.Conclusion:Hyperviscositemia had a strong correlation with the pathogenesis of elderly hypertension.Red cell deformability and viscosity abnormality play an important role in the pathogenesis of hypertension.Using medicine which can improve the hemorheological condition shows remarkable help to elderly hypertension.