40例新生儿围生期巨细胞病毒感染的临床分析

Clinical analysis of 40 neonates with perinatal cytomegalovirus infection

目的:探讨围生期新生儿巨细胞病毒感染的临床特点。方法:对外周血CMV-PP65抗原阳性并伴有临床症状的40例新生儿进行临床分析。结果:①临床表现为肝脏损害:肝脏增大26例,黄疸延迟16例,便白11例,尿黄10例,肝功能改变者40例,体重不增7例;肺损伤:发热15例,咳嗽10例,呼吸促11例,胸片双肺纹理增强11例。②血液系统改变:白细胞数减少7例,贫血27例,血小板减少16例。结论:围生期新生儿巨细胞病毒感染主要表现以肝脏损伤多见,其次为血液系统和肺损伤。

Objective： To investigate clinical features of the neonates with perinatal cytomegalovirus infection. Methods： To do the clinical analysis of the newborn associated with peripheral blood CMV - PP65 antigen - positive and clinical symptoms. Results： Clinical manifestations of liver damage： hepatomagely in 26 cases, jaundice delay to fade in 16 cases, pale stool in 11 cases, yellow urine in 10 cases, liver function damage in40 patients, weight gain poorly in 7 cases; Lung injury： fever in 15 cases, cough in 10 cases , tachypnea in 11 cases, increased pulmonary markings of chest X - ray in 11 cases ; Blood system changes ： reduction of the number of white blood cells in 7 cases, anemia in 27 cases, thrombocytopenia in 16 cases. Conclusion ： The clinical feature of perinatal cytomegalovirus infection in newborn mainly include liver damage, followed by the blood system and lung injury.