同期缩野超分割放疗毒副反应的观察及护理

observation and Nursing of the Toxic Effect of the concomitant Boost Radiotherapy

将108例鼻咽癌患者随机分为两组（各54例），实验组采用同期缩野超分割放疗；对照组采用常规放疗方法。结果表明：实验组疗效明显高于对照组，放疗结束时和放疗后3个月，实验组鼻咽肿瘤全消率均为92．67％．颈淋巴结全消率为71．1％和97．4％。对照组鼻咽肿瘤全消率为74．1％和75．9％，颈淋巴结全消率为42．1％和0．5％；CT疗效Ⅰ级：实验组为51.9％，对照组为25．9％。P＜0.05。毒副反应：皮肤反应，Ⅲ度皮炎实验组为24．1％，对照组为12．9％；口咽粘膜反应，Ⅲ度粘膜反应实验组59．3％，对照组40．7％。P＜0．05。两组均未出现Ⅳ度皮肤反应及Ⅳ度日咽粘膜反应，均未中断放疗。

108 cases of nasopharyngeal carcinoma were rondomly divided into 2 group.experiment group and control group,each of which consisted of 54 cases.Concomitant Boost Radiotherapy was applied to control group.The result showed that curative ef-fect of expect of experiment group was significantly better that of control group. At the end of nad at after 3months of radiotherapy,clear rates of nasapharyngeal carcinoma in experiment group were both 92.6% and clear rates of cervicel lymph node were 71.7%,97.4% respectiverly.Clear rates of nasapharyngeal carcinoma in control group were 74. 1% and 75.9% and cervical lymph node clear rates were 42.1%,60.5%.CT confirmed curative effect degree Ⅰ:experiment group,51.9%, control group,25.9%, P＜0.05. Txcic effect:skin reaction,degree Ⅲ dermatitis,experiment group,24.1%, control group,12.9% oral mucosa reaction, Ⅲdegree,experiment group 59.3%,conrtol group 40.7%, P＜0.05. Ⅳ degree of skin reaction and Ⅳ degree of oral mucosa reaction did not appear in either of the two group. There were no interruption during radiotherapy.