无机陶瓷膜精制川芎水提液的实验研究

Study on Refinement of Aqueous Extract of Rhizoma Chuanxiong with Inorganic Ceramic Membrane

目的考察不同孔径陶瓷膜微滤在川芎水提液纯化中的作用,确定最佳孔径微滤膜。方法采用50nm、200nm、500nm孔径的无机陶瓷膜对川芎水提液进行微滤,对水提液微滤前后性状、总固体、有效成分等进行对比分析。结果川芎水提液微滤前为浑浊液体,三种孔径无机陶瓷膜微滤后均为颜色变浅的澄清液体,总固体去除率分别为25.7%,26.5%,25.9%,阿魏酸损失率分别为12%,6%,4%。结论通过三批中试验证,干固物收率、阿魏酸的量均稳定,表明200nm孔径陶瓷膜应用于川芎水提液的纯化精制工艺是可行的。

Objective To observe the microfihration of different types of ceramic membrane for aqueous extract oi Rhizoma Chuanxiong, and to select the optimal type of ceramic membranes. Methods The aqueous extract of Rhizoma Chuanxiong was microfiltered by inorganic ceramic membranes in the pore diameter of 50 nm, 200 nm, and 500 nm, respectively. The characters, total solids, and active ingredients of the aqueous extract were analyzed and compared before and after mierofiltration. Results The aqueous extract turned into clarified liquid from turbid liquid after microfihration with the three types of the inorganic ceramic membrane. The removal rate for total solids was 25.7 % , 26.5 % and 25.9 % , and the loss rate for ferulic acid was 12 % , 6 % and 4 % , respectively for the inorganic ceramic membranes in the pore diameter of 50 nm, 200 nm, and 500 nm. ConcLusion Both the yield of dry solid material and ferulie acid are stable during the three middle - scale tests, indicating that the aperture ceramic membrane in the pore diameter of 200 nm is a optimal selection for the purification and refining of aqueous extract of Rhizoma Chuanxiong.