亚甲蓝染色指导在Barrett食管病理诊断中的意义

Clinical value of methylene blue-directed biopsies in pathologic diagnosis of Barrett's oesophagus

Barrett食管是食管腺癌的癌前病变。随着食管腺癌发病率的增加,Barrett食管的病理诊断越发受到重视。本文对84例Barrett食管的患者随机分为实验组和对照组,分别采用亚甲蓝染色指导活检和四象限活检,分析病理结果,对两组诊断率和活检数目阳性率进行比较。结果显示亚甲蓝染色指导活检对Barrett食管的病理诊断有重要价值,为今后的Barrett食管内镜活检病理诊断提供理论指导。

Barrett＇s esophagus is a precancerous lesion of esophageal adenocarcinoma.With the increasing incidence of esophageal adenocarcinoma,pathological diagnosis of Barrett＇s esophagus attaches more attention.In this study,84 cases of Barrett＇s esophagus were randomly divided into experimental and control groups.In experimental group,staining was performed with 0.5% solution of methylene blue with a spray catheter.In control group,four-quadrant random biopsies were taken during routine endoscgrope.Finally,the clinical value of methylene blue-directed biopsies in pathologic diagnosis of Barrett＇s esophagus was evaluated.It provides theoretical guidance for endoscope biopsy diagnosis of Barrett＇s esophagus.