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胆碱酯酶抑制药治疗阿尔茨海默病 被引量:8

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摘要 阿尔茨海默病患者胆碱能受体功能低下,导致认知障碍,胆碱酯酶抑制药通过抑制胆碱酯酶,抑制乙酰胆碱降解,改善认知功能,但也可伴拟胆碱能不良反应(如恶心、呕吐和腹泻)。非那西汀抑制1A2酶,抑制石杉碱甲代谢70%。
作者 喻东山
出处 《医药导报》 CAS 2010年第2期186-189,共4页 Herald of Medicine
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