摘要
联合检测血清CA125、CA72-4与CEA水平对卵巢癌早期诊断的价值。对112例卵巢癌患者,185例卵巢良性肿瘤患者及对照组100名健康妇女,应用电化学发光免疫法测定血清CA125、CA72-4与CEA水平,然后进行统计分析。结果表明:健康妇女组和卵巢肿瘤组比较,卵巢癌组患者血清CA125、CA72-4与CEA水平及阳性率明显升高(P<0.01),三项标志物的阳性率分别为86.61%,67.86%,49.11%,三项联合检测阳性率为91.96%。血清CA125、CA72-4与CEA联检可以提高卵巢癌早期诊断的阳性率,对卵巢肿瘤的良恶性辅助诊断及鉴别诊断具有一定应用价值。
To explore the clinical values of combined detection of serum CA125,CA72-4 and CEA levels in the early diagnosis of ovarian cancer,the serum CA125,CA72-4 and CEA levels in 112 patients with ovarian cancer,185 patients with benign ovarian tumor and 100 healthy women controls were measured by electrochemical luminescence immunoassay(ECLIA).The results showed that serum CA125,CA72-4 and CEA levels and positive rate in patients with ovarian cancer were significantly higher that of in patients with benign ovarian tumor and healthy controls(P〈0.01).The positive rates of CA125,CA72-4 and CEA in patients with ovarian cancer were 86.61%,67.86% and 49.11%,respectively.The positive rate of three markers combined detection was 91.96%.The combined detection of the three markers may increase the positive rate in the early diagnosis of ovarian cancer,and help to differentiate the benign and malignant ovarian tumor.
出处
《标记免疫分析与临床》
CAS
2010年第1期7-9,共3页
Labeled Immunoassays and Clinical Medicine