2Leach MJ, Marden CM, Miller AA. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug, Ⅱ : neurochemical studies on the mechanism of action[J]. Epilepsia, 1986 ;27:490 - 497.
3Xie X, Lancaster B, Peakman T, et al. Interaction of the antiepileptie drug lamotr/g/ne with recombinant rat brain type Ⅱ A Na channelsand with native Na channels in rat hippocampal neurons [ J ] . Pflugers Arch, 1995,30 : 37 - 46.
4Armijo TA, shushtarian M, valdizan EM, et al. Ion channels and epilepsy [ J ]. Curt Pharm Des, 005,11 ( 5 ) : 2975 - 2003.
6TArifH, Svoronos A, Resor SP, Jr, et al. Tile effect of age and comedication on lamotrigine clearance, tolerability, and efficacy[ J ]. Epilepsia, 2011, 52 (10) : 1905-1913.