摘要
目的:探讨超敏C反应蛋白(HscRP)检测在小儿细菌性肺炎、病毒性肺炎和支原体肺炎诊断中的临床意义。方法:采用免疫透射比浊法测定血清C反应蛋白浓度值,同时做支原体和细菌培养及白细胞(WBC)计数和分类。结果:102例细菌性肺炎肺炎患者中(A组)HSCRP〉8mg/L,阳性率为94.12%;58例支原体患者中(B组)阳性率为89.55%;65例病毒性肺炎患者(C组)中阳性率为10.77%;40例健康对照组(D组)中阳性率为7.50%。A、B组与D组阳性率差异性显著(P〈0.01);而C组与D组相比无显著性差异(P〉0.05)。A、D两纽临床治愈后复查HSCRP水平与治疗前浓度差异显著(P〈0.05)。结论:HSCRP检测在小儿肺炎急性期诊断鉴别中有辅助作用,对临床用药有一定指导意义。
objective:Study the high- sensitivity C- reactive protein (HSCRP) detection to children with bacterial pneumonia, viral pneumonia and mycoplasma pneumonia for the diagnosis of clinical significance. Methods : serum C - reactive protein concentration was tested by Immunohistochemical transmission turbidimetry , while doing Mycoplasma and bacterial culture and white blood cell (WBC) count and classification. Result: 102 patients with bacterial pneumonia (A group) HSCRP 〉 3mg/L, the positive rate was 97% ;58 patients with viral pneumonia (B group) , the positive rate was 92% ; 65 patients with mycoplasma pneumonia( C group), the positive rate was 16.8% ; 40 cases of normal children, the positive rate was 6.4%. A, B two sets of results and D group resuhs is significant difference ( P 〈 0. 01 ) ; but C group results and D group results is not significant difference( P 〉 0.05 ) o conclusion: HSCRP detection can helping to diagnosis of the children with pneumonia and the clinical use of drugs have some guiding significance.