摘要
目的对比短时效阿片类药物-瑞芬太尼与芬太尼对小儿斜视术后呕吐和疼痛的作用的差别。方法60名ASAI～II级,2～12岁择期在全麻下行斜视纠正术的小儿,随机分为两组,R组(瑞芬太尼)与F组(芬太尼)。术后记录25 h呕吐事件。苏醒后60 min记录疼痛评分。结果两组术后呕吐发生率没有统计学差异(49%vs 48%)。但是R组术后呕吐频率较F组低(0.95 vs 2.2)。苏醒后头30 min,F组术后疼痛评分较低。结论平衡全麻下小儿斜视术后,瑞芬太尼组术后呕吐发生频率较少,但芬太尼组对术后早期镇痛效果较好。
Objective To compare the effect of remifentanil with fentanyl on postoperative vomiting and pain in children undergoing strabismus surgery. Methods 60 ASA status Ⅰ or Ⅱ children from 2 - 12 years undergoing elective strabismus surgery under general anesthesia. Children were randomized to receive either remifentanil （ Group R） or fentanyl （ Group F）. POV episodes were recorded for 25 hour. pain scores were ob- tained by using an objective pain scale for 60 min during recovery. Results The number of patients who expe- rienced POV did not differ significantly between groups（49% vs 48% ）. However, in the group R, POV epi- sodes were significantly less frequent（0. 95 vs 2.2）. In contrast, fentanyl was associated with lower pain scores during the first 30 rain of recovery. Conclusion Child undergoing strabismus surgery under balanced anesthe- sia with remifentanil, compared with fentanyl, shows less frequent POV. However, early postoperative analgesia is better with fentanyl.
出处
《中国实用医药》
2010年第1期41-42,共2页
China Practical Medicine
