106例新生儿惊厥临床分析

Clinical analysis of 106 neonatal convulsions

目的分析探讨新生儿惊厥的病因及与围产期的关系。方法回顾性分析106例新生儿惊厥的病因、发病时间、发作形式、转归和相应的实验室检查。结果HIE、颅内出血是新生儿惊厥的主要病因,其中HIE、颅内出血多在出生后3天内发病,而低钙血症、感染多在出生3天后发病、遗传代谢性疾病则出现时间不确定,但治疗后惊厥仍反复出现是其特点,另外106例患儿中68例存在围产期高危因素。结论新生儿惊厥是多种原因引起的新生儿期常见症状,对常规治疗后又反复出现惊厥的新生儿应多考虑遗传代谢性疾病;围产期高危因素易导致惊厥发生,因而应加强围产期保健,对有围产期高危因素的新生儿应重点监护。

Aim To analyze and to explore the etiology of neonatal convulsions, and the relation between neonatal convulsions and perinatal. Methods Etiology, onset time, onset stytle, prognosis and relative examination of 106 neonatal convulsions cases were analyzed retrospectively. Results HIE and intracranial hemorrhage are the major etiology for neonatal convulsions. HIE and intracranial hemorrhage are onset in 3 days after birth, but hypocalcemia and infection attack more than 3 days after birth. The onset time of hereditary matabolic disease is not confirmed ,but this disease is recurrent. Besides ,68 cases of 106 neonatal convulsions cases have perinatal high-risk factors. Conclusions The neonatal convulsion is various familiar symptoms in newborn, perinatal factor are mostly in clinic. Hereditary matabolie disease should be referred ,when neonatal convulsions is recurrent after routine treatment. Perinatal high-risk factors can easily cause neonatal convulsions, so perinatal healthcare should be strengthened, and the newborns who have perinatal high-risk factors should be intensive cared.