电视腹腔镜卵巢打孔治疗多囊卵巢综合征不孕患者22例临床分析

Clinical analysis on 22 infertile women with polycystic ovary syndrome treated by laparoscopic ovarian drilling

目的:探讨电视腹腔镜手术治疗多囊卵巢综合征(PCOS)不孕患者的临床疗效。方法:取2008年5月～2009年6月广州市妇女儿童医院妇科确诊PCOS患者进行电视腹腔镜下卵巢打孔术及输卵管通液术,手术前后分别测定血清黄体生成素(LH),卵泡刺激素(FSH),雄激素(T)水平,术后检测排卵情况,妊娠率及妊娠结果。结果:术后的LH及T水平较术前有显著下降,FSH及PRL水平无明显变化,术后有19例患者发生排卵,13例成功妊娠,3例在加用CC后排卵但未妊娠。结论:腹腔镜卵巢打孔术能明显改善CC抵抗PCOS患者的排卵和受孕机会,但打孔数多于8个有卵巢早衰可能,应控制在4～6个或以下,该方法可以推广应用。

Objective ： To explore the clinical efficacy of laparoscopic ovarian drilling in treatment of infertile women with polyeystic ovary syndrome （PCOS） . Methods： From May 2008 to June 2009, women diagnosed as PCOS underwent laparoscopic ovarian drilling and hydrotubation, the serum levels of luteinizing hormone （LH）, follicle stimulating hormone （FSH） and androgen （T） before and after operation were detected, ovulation, pregnancy rate and pregnancy outcomes after operation were recorded. Results ： The serum levels of LH and T after operation were significantly lower than those before operation, but there was no difference in serum levels of FSH and PRL before and after operation. After operation, 19 women ovulated, 13 women got pregnancy successfully, and 3 women ovulated after administrated by clomiphene, but got no pregnancy. Conclusion： Laparoscopie ovarian drilling can increase the ovulation rate and pregnancy rate significantly in patients with clomiphene - resistant PCOS.