摘要
目的探讨人博卡病毒(HBoV)与慢性阻塞性肺疾病急性加重(AECOPD)的关系。方法PCR检测2008年11月～2009年4月55例慢性阻塞性肺疾病(COPD)患者诱导痰标本的HBoV,其AECOPD患者26例(47.3%),稳定期COPD患者29例(52.7%)。结果共发现2例HBoV阳性,AECOPD患者和稳定期COPD患者各1例,阳性率分别为3.85%和3.45%。结论HBoV不是AECOPD呼吸道感染的的重要病原,双者之间无关联性。
Objective To determine the frequency and clinical relevance of HBoV infection in adult patients with acute exacerbation of chronic obstructive pulmonary disease （AECOPD）. Methods We retrospectively tested 55 COPD patients, 26 （47. 3% ） with AECOPD and 29 （52. 7% ） with stable disease, of whom induced sputum had been obtained for the presence of HBoV deoxyribonucleic acid （DNA）. Results HBoV DNA was detected in two patients （3.64%）. Of those, one patient had AECOPD. Thus, the frequency of HBoV infection demonstrated to be low in both AECOPD （3.85%） and stable COPD （3.45%）. Conclusion HBoV detection is infrequent. A major role of HBoV infection in adults with AECOPD is unlikely.
出处
《临床肺科杂志》
2010年第3期313-314,共2页
Journal of Clinical Pulmonary Medicine
关键词
人博卡病毒
慢性阻塞性肺疾病
急性加重
急性呼吸道感染
human bocavims
chronic obstructive pulmonary disease
acute exacerbation
acute respiratory tract infection
