DGAT基因在畜禽育种中的应用

Application of DGAT Gene in Poultry and Livestock Breeding

DGAT是一种甘油酰基转移酶(Diacylgycerol Acyltransferase,DGAT),该酶与脂肪代谢、脂类在组织中的沉积有很大关系,它的主要作用机制是使二酰甘油加上脂肪酸酰基形成三酰甘油。编码该酶的基因有DGAT1和DGAT2,前者属于ACAT基因家族,后者属于DGAT2基因超家族。综述了DGAT基因定位、结构、生物学效应及在畜禽育种上的应用,并对DGAT基因在畜禽育种中的应用前景进行了探讨。

DGAT is a glycerol acyltransferase （Diacylgycerol Acyltransferase, DGAT）, it relates with fat metabolism and lipid deposition in tissues, its main interaction mechanism is add acyl of fatty acid to diacylglycerol to form triacylglycerol. The genes DGAT1 and DGAT2 could encode the acyltransferase, the former belongs to ACAT gene family, and the later belongs to DGAT2 gene superfamily. The paper reviewed the location, structure, biological effects and applications of DGAT gene in animal breeding, and also discussed its application prospect in Poultry and livestock breeding.