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蛋白酶激活受体-2与胃肠道运动和感知的研究进展 被引量：2

Research advances of PAR-2 and gastrointestinal motility
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摘要 蛋白酶激活受体-2(proteinase-activated receptor,PAR)是G蛋白耦联受体家族成员之一,遍布整个胃肠道上皮细胞表面,易暴露于能使其激活的蛋白酶中,是体内许多消化道腺体外分泌的直接调控者,直接影响胃肠道动力。目前,蛋白酶激活受体独特的激活方式及其在消化系统中的广泛分布和复杂多样的生理作用,特别是蛋白酶激活受体-2与胃肠运动和感知的关系正受到广泛关注。 Proteinase activation receptor-2 （PAR-2） is one of the G protein coupling receptor family members. It exists in all over the epithelial cell surface of gastrointestinal tract, and is easy to expose to the proteinase that can activate it. It is a direct exocrine regulator of many digestive glands, arid directly affects the capability of gastrointestinal tract. At present, the PAR-2＇s unique activation way, its wide distribution in digestive system and its complicated physiological functions, especially the relation between PAR-2 and the gastrointestinal movement and perception, are being highly concerned.
作者 海鸥 谢立群
机构地区 中国人民武装警察部队医学院附属医院消化内科
出处 《医学研究生学报》 CAS 2010年第1期97-101,共5页 Journal of Medical Postgraduates
基金 武警医学院科研基金(WBS2007-1)
关键词 蛋白酶激活受体-2 胰蛋白酶 胃肠道 运动 感知 Proteinase activation receptor-2 Proteinase Gastrointestinal tract Movement Perception
分类号 R333 [医药卫生—人体生理学]
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参考文献30

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同被引文献26

  • 1季洪赞,吴晓尉,许小兵,孙泉,刘瑜,张立,赵文新,于正洪,张志良,龚维忠,郑雷.匹维溴胺治疗老年人功能性肠道障碍的临床疗效及生活质量评估[J].中国组织工程研究与临床康复,2007,11(12):2275-2278. 被引量：6
  • 2季洪赞,吴晓尉,许小兵,孙泉,刘瑜,张立,赵文新,于正洪,张志良,龚维忠,郑雷.老年人功能性肠道障碍与高血压靶器官损害相关性研究[J].中国慢性病预防与控制,2007,15(4):365-366. 被引量：8
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医学研究生学报
2010年 第1期

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