脂联素与类风湿关节炎的研究进展
摘要
脂联素(adiponectin)是脂肪细胞分泌的一种脂肪因子,除糖尿病、动脉粥样硬化等疾病外,其与炎性关节病,如类风湿关节炎(rheumatoid arthritis,RA)也存在显著联系,而其具体机制尚不清楚。
出处
《中华风湿病学杂志》
CAS
CSCD
北大核心
2010年第1期64-66,共3页
Chinese Journal of Rheumatology
参考文献18
-
1王新华,王士雯.脂联素与冠心病及其危险因素的关系[J].中华老年多器官疾病杂志,2006,5(4):310-313. 被引量:2
-
2Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature, 2003, 423 : 762-769.
-
3Hug C, Wang J, Ahmad NS, et al. T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/ adiponectin. Proc Natl Acad Sci USA, 2004, 101: 10308-10313.
-
4Ushiyama T, Chano T, Inoue K, et al. Cytokine production in the infrapatellar fat pad: another source of cytokines in knee synovial fluids. Ann Rheum Dis,. 2003, 62:108-112.
-
5Schaffler A, Ehling A, Neumann E, et al. Adipocytokines in synovial fluid. J Am Med Assoc, 2003, 290: 1709-1710.
-
6Presle N, Pottie P, Dumond H, et al. Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis: contribution of joint tissues to their articular production. Osteoarthritis Cartilage, 2006, 14: 690-695.
-
7Senolt L, Pavelka K, Housa D, et al. Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis. Cytokine, 2006, 35: 247-252.
-
8Ehling A, Schaffler A, Herfarth H, et al. The potential of adiponectin in driving arthritis. J Immunol, 2006, 176: 4468-4478.
-
9Ebina K, Fukuhara A, Ando W, et al. Serum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction. Clin Rheumatol, 2009, 28: 445-451.
-
10Gonzalez-Gay MA, Llorca J, Garcia-Unzueta MT, et al. High- grade inflammation, circulating adiponectin concentrations and cardiovascular risk factors in severe rheumatoid arthritis. Clin Exp Rheumatol, 2008, 26: 596-603.
二级参考文献30
-
1[1]Scherer PE,Williams S,Fogliano M,et al.A novel serum protein similar to Clq,produced exclusively in adipocytes.J Biol Chem,1995,270:26746-26749.
-
2[2]Hu E,Liang P,Spiegelman BM.AdipoQ is a novel adipose-specific gene dysregulated in obesity.J Biol Chem,1996,271:10697-10703.
-
3[3]Maeda K,Okubo K,Shimomura I,et al.cDNA cloning and expression of a novel adipose specific collagen-like factor,apM1 (Adipose Most abundant Gene transcript 1).Biochem Biophys Res Commun,1996,221:286-289.
-
4[4]Nakano Y,Tobe T,Choi-Miura NH,et al.Isolation and characterization of GBP28,a novel gelatin binding protein purified from human plasma.J Bio Chem,1996,120:803-812.
-
5[5]Saito K,Tobe T,Minoshima S,et al.Organization of the gene for gelatin-binding protein (GBP28).Gene,1999,229:67-73.
-
6[6]Stumvoll M,Tschritter O,Fritsche A,et al.Association of the T2G polymorphism in adiponectin (exon 2)with obesity and insulin sensitivity:interaction with family history of type 2 diabetes.Diabetes,2002,51:37-41.
-
7[7]Takahashi M,Funahashi T,Shimomura I,et al.Plasma leptin levels and body fat distribution.Horm Metab Res,1996,28:751-752.
-
8[8]Maeda N,Takahashi M,Funahashi T,et al.PPAR γ ligands increase expression and plasma concentration of adiponectin,an adipose-derived protein.Diabetes,2001,50:2094-2099.
-
9[9]Hug C,Wang J,Ahmad NS,et al.T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin.Proc Natl Acad Sci USA,2004,101:10308-10313.
-
10[10]Liu YM,Lacorte JM,Viguerie N,et al.Adiponectin gene expression in subcutaneous dipose tissue of obese women in response to short-term very low calorie diet and refeeding.J Clin Endocrinol Metab,2003,88:5881-5886.
-
1马文彬.痛风性关节炎的诊断和处理[J].中国农村医学杂志,2004,2(3):75-78.
-
2尹佳,时骏.风湿免疫病诊治存在误区[J].中国社区医师(医学专业),2007,9(18):45-45.
-
3邱楠,杨新新,赵肖敏,王欣,黄烽.布鲁杆菌病误诊为炎性关节病3例报告及文献复习[J].解放军医学院学报,2015,36(12):1240-1242. 被引量:3
-
4张卓莉,李光韬.核磁共振技术在炎性关节病诊治中的重要意义[J].北京大学学报(医学版),2012,44(2):171-175. 被引量:1
-
5邓小虎,黄烽.英夫利西单抗治疗炎性关节病的研究进展[J].中国药物应用与监测,2006,3(6):10-14. 被引量:17
-
6贾捷婷,李慧,李国青,魏华,张育.Th17/Treg细胞在炎性关节病的免疫调节作用[J].中华临床免疫和变态反应杂志,2011,5(3):233-237. 被引量:8
-
7张莉芸.己酮可可碱治疗炎性关节病的机制和前景展望[J].临床药物治疗杂志,2005,3(4):31-36. 被引量:2
-
8Edward Roddy,叶夏,张卓莉.痛风[J].英国医学杂志中文版,2014(3):180-186.
-
9赵芳芳,温鸿雁,张军锋.微小RNA在类风湿关节炎骨破坏中的研究进展[J].中华风湿病学杂志,2016,20(9):629-632.
-
10唐光阳.老年类风湿性关节炎的中西医结合治疗(附32例报告)[J].中国医学文摘(老年医学),2005,14(2):136-137. 被引量:1