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与川崎病相关的基因多态性研究进展 被引量:10

Research Progress of Gene Polymorphism Related with Kawasaki Disease
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摘要 川崎病(KD)的病因不清,目前仍倾向于感染因素,但大量的流行病学资料显示KD的发病具有一定的遗传背景。为此,通过检索和分析了近几年与KD相关的基因多态性的论文,现对血管紧张素转换酶基因多态性、一氧化氮合酶基因多态性、细胞因子基因多态性等问题作一综述。 The pathogen of Kawasaki disease ( KD ) is still unknown although infection is considered as the most possibility factor. However epidemiologic studies showed that genetic background might be a main factor in the onset of KD. The recent papers on gene polymorphism including angiotensin - convertion enzyme, nitric oxide synthase and eytokine related with KD were searched and analyzed in this review.
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2010年第1期60-62,共3页 Journal of Applied Clinical Pediatrics
基金 国家自然科学基金(30973238) 北京自然科学基金(7092032) 北京自然科学基金B类/北京教育委员会重大科研项目(KZ201010025-024) 首都医学发展科研基金重点项目(2007-2063) 首都医科大学基础临床联合项目(2007JL48)
关键词 川崎病 基因 病因 Kawasaki disease gene etiology
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参考文献29

  • 1Chang RK. Epidemiologie characteristics of children hospitalized for Kawasaki disease in California[ J l. Pediatr Infect Dis J, 2002,21 ( 12 ) : 1150-1155.
  • 2Holman RC,Curns AT, Belay ED,et al. Kawasaki syndrome in Hawaii [ J ]. Pediatr Infect Dis J,2005,24 ( 5 ) :429 - 433.
  • 3Heaton P,Wilson N, Nicholson R, et al. Kawasaki disease in New Zealand [ J ]. J Paediatr Child Health, 2006,42 ( 4 ) : 184 - 190.
  • 4Fujita Y, Nakamura Y, Sakata K, et al. Kawasaki disease in families [ J ]. Pediatrics, 1989,84 (4) :666 - 669.
  • 5Harada F, Sada M, Kamiya T, et al. Genetic analysis of Kawasaki syndrome[J]. Am J Hum Genet,1986,39( 4 ) :537 -539.
  • 6Rigat B, Hubert C, Alhenc - Gelas F, et al. An insertion/deletion polymorphism in the angiotensin Ⅰ - converting enzyme gene accounting for half the variance of serum enzyme levels [ J ]. J Clin Invest, 1990,86 (4) :1343 - 1346.
  • 7Tiret L, Rigat B, Visvikis S. Evidence, from combined segregation and linkage analysis,that a variant of the angiotcnsin Ⅰ - converting enzyme (ACE) gene controls plasma ACE levels [ J ]. Am J Hum Genet, 1992, 51(1) :197 -205.
  • 8万根平,顾晓琼,曾华松,黄式文.ACE基因多态性及血清ACE水平与儿童川崎病相关性[J].广东医学,2006,27(10):1543-1544. 被引量:8
  • 9刘东海,王秀英,许毅.血管紧张素转换酶基因多态性与川崎病的相关性[J].实用儿科临床杂志,2005,20(1):48-50. 被引量:4
  • 10Takeuchi K, Yamamoto K, Kataoka S,et al. High incidence of angiotensin Ⅰ converting enzyme genotype Ⅱ in Kawasaki disease patients with coronary aneurysm [ J ]. Eur J Pediatr, 1997,156 (4) : 266 - 268.

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