百草枯中毒胸部CT表现与临床评价

Radiographic and Clinical Evaluation of chest CT scan on Paraquat-induced Pulmonary Damage

目的探讨螺旋CT对百草枯中毒肺损伤的影像学特征及临床意义。方法回顾分析18例百草枯中毒患者的胸部CT表现。结果18例患者中有5例存活3周以上，中毒早期8例胸部无明显异常，磨玻璃样改变10例；中毒中期10例见两肺弥漫磨玻璃样密度影，出现渗出病变5例，实变3例，胸腔积液2例。中毒晚期8例表现不同程度肺间质纤维化和肺蜂窝样改变，3例伴牵引性支气管扩张，胸腔积液1例，2例无明显异常。结论CT诊断对病情发展、演变及估计预后、指导临床治疗具有重要意义。

Objective To investigate the CT feature and clinic significance of Paraquat-induced Pulmonary Damage. Methods CT data of chest in 18 patients with paraquate poisoning were retrospectively analyzed. Results 5 patients of 18 survived over 3 week. In the early period,in 10 of them, the predominate findings were glass density;while the other 8 cases shomed normal. In the middle period,extensive glass density were found in 10 cases,exudation in 5 cases,consolidation in 3 cases with hydrothorax 2 cases. In the late period,pulmonary firbrosis and microeyst formation in different degree were shown in 8 cases,3 cases combined with bronchiectasis, hydrothorax in 1 case ; while the other 2 cases shomed normal. Conclusion Chest CT has great advantage in progression of paraquate-induced pulmonary damage and has important significance in conduction of clinic therapy, evaluation of prognosis.