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心肌缺血再灌注损伤信号分子p38MAPK的研究进展 被引量:15

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作者 陈冰心 任澎
出处 《心肺血管病杂志》 CAS 2010年第1期68-70,共3页 Journal of Cardiovascular and Pulmonary Diseases
基金 新疆自治区自然科学基金资助(200821117)
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参考文献10

  • 1Johns DG, Ao Z, Willette RN,et al. Role of p38 MAP kinase in postcapillary venule leukocyte adhesion induced by ischemia/reperfusion injury. Pharmacol Res, 2005,51:463-471.
  • 2Jaswal JS, Gandhi M, Finegan BA,et al. Inhibition of p38 MAPK and AMPK restores adenosine-induced cardioprotection in hearts stressed by antecedent ischemia by altering glucose utilization. Am J Physiol Heart Circ Physiol,2007,293 : HI 107-1114.
  • 3Brady NR, Hamacher-Brady A, Gottlieb RA. Proapoptotic BCL-2 family members and mitochondrial dysfunc- tion during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors. Biochim Biophys Acta ,2006,1757:667-678.
  • 4Wang M, Baker L, Tsai BM,et al. Sex differences in the myocardial inflammatory response to ischemia-reperfusion injury. Am J Physiol Endocrinol Metab, 2005, 288 : E321-326.
  • 5Jin JK, Whittaker R, Glassy MS,et al. Localization of phosphorylated alphaB-crystallin to heart mitochondria during isehemia-reperfusion. Am J Physiol Heart Circ Physiol, 2008,294 : H337-344.
  • 6Ruusalepp A, Czibik G, Flateb T, et al. Myocardial protection evoked by hyperoxic exposure involves signaling through nitric oxide and mitogen activated protein kinases. Basic Res Cardiol,2007,102:318-326.
  • 7Peart JN, Gross ER, Headrick JP,et al. Impaired p38 MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection. J Mol Cell Cardiol, 2007,42:972-980.
  • 8Mukherjee S, Lekli I, Das M, et al. Cardioprotection with alpha-tocopheryl phosphate: amelioration of myocardial ischemia reperfusion injury is linked with its ability to generate a survival signal through Akt activation. Biochim Biophys Acta, 2008,1782: 498-503.
  • 9Kim JK, Pedram A, Razandi M, et al. Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoforms. J Biol Chem ,2006 ,281:6760-6767.
  • 10Simoncikova P, Ravingerova T, Baranelk M. The effect of chronic doxorubicin treatment on mitogen-activated protein kinases and heat stress proteins in rat hearts. Physiol Res ,2008,57 : S97-S102.

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