鲍氏不动杆菌感染株耐药性分析

Acinetobacter baumannii Infection:A Drug Resistance Analysis

目的分析医院鲍氏不动杆菌感染株的耐药性。方法用常规细菌培养方法从患者标本中分离出细菌,采用ATB细菌仪鉴定菌种,用K-B法对常用抗菌药物进行体外敏感测定。结果3年中共分离出鲍氏不动杆菌655株(无重复菌株),其中2006年139株,2007年174株,2008年342株;药敏试验结果表明除亚胺培南、头孢哌酮/舒巴坦外,氨苄西林、头孢西丁、复方新诺明、头孢他啶、氨曲南和庆大霉素3年的耐药率均>50.0%,其中泛耐药株占61.8%。结论鲍氏不动杆菌耐药率高,应严格各项无菌操作制度,加强药敏检测,提倡合理使用抗菌药物,防止医院感染暴发流行。

OBJECTIVE To analyze the drug resistance of Acinetobacter baumannii isolates. METHODS Bacteria were got from specimens of patients and identified with ATB and the commonly used antibiotic were tested by K-B method. RESULTS There were 655 ABA strains isolated （without duplicate strain） during from 2006 to 2008, ie, 139 in 2006, 174 in 2007, and 342 in 2008. The sensitivity test result indicated that except imipenem and cefoperazone/sulbactam the drug-resistance rate of other antibiotics was higher than 50.0~. And pan-resistant bacteria were 61.8%. CONCLUSIONS The drug resistance of ABA rate is high. We should execute the aseptic operation strictly, strengthen the drug sensitivity examination, advocate the reasonable use of antibiotics, and prevent the outbreak.