含环糊精的温度敏感性聚合物的合成及自组装

Synthesis and Self-assembly of Thermo-sensitive β-Cyclodextrin Containing Copolymers

合成了侧基含环糊精的聚异丙基丙烯酰胺(PnipamCD),该聚合物在水溶液中具有较高的最低临界溶解温度(LCST).快速升温到溶液的LCST以上可形成球形胶束,慢速升温到LCST以上可形成空心囊泡.在PNIPAM的选择性溶剂中,PnipamCD形成棒状组装体.

A novel thermo-sensitive β-eyelodextrin pendent poly （ N-isopropylaerylamide ） （ PnipamCD ） was prepared, which had a higher lower critical solution temperature（LCST） than that of pure poly（N-isopropylacrylamide） （PNIPAM）. In its aqueous solution, spherical mieelles were obtained as temperature increased rapidly while hollow vesicles were obtained as temperature increased slowly. In addition, rod-like aggregates were achieved in acetone, a selective solvent of PNIPAM.