小剂量尿毒清颗粒联合灌肠液治疗老年慢性肾功能衰竭的疗效观察

Efficacy Observation of Small Dose of Uremic Clearance Granule Combined with Colon Enema in the Treatment of Aged Patients with Chronic Renal Failure

目的:观察小剂量尿毒清颗粒联合灌肠液对老年慢性肾功能衰竭(CRF)的影响。方法:将60例老年CRF患者随机分为治疗组(30例)和对照组(30例),2组均给予一定的基础治疗,治疗组在基础治疗上加服尿毒清颗粒联合灌肠液,对照组在基础治疗上加服药用炭;15d为一疗程,30d后对比2组疗效。结果:治疗组在治疗30d后临床症状明显改善,血尿素氮(BUN)、血肌酐(Scr)、血尿酸(UA)、血钾(K+)均显著下降。结论:小剂量尿毒清颗粒口服联合灌肠液保留灌肠治疗老年慢性肾功能衰竭疗效显著,方便易行,依从性好。

OBJECTIVE： To observe the efficacy of small dose of uremic clearance granule combined with colon enema on aged patients with chronic renal failure （CRF）. METHODS： 60 aged CRF patients were randomly divided into treatment group（n= 30）and control group （n=30）, Two groups were given essential treatment. Control group were treated with medicinal carbon addi- tionally. Treatment group were additionally treated with uremic clearance granule （p.o.） combined with colon enema. The course of treatment was 15 days and curative effects were compared between two groups after 30 days of treatment. RESULTS： 30 days later clinical symptom of patients in treatment group was obviously improved and the levels of blood urea nitrogen, serum creatinine, blood uric acid and serum potassium were lower than before treatment with significant difference. CONCLUSION： Small dose of uremic clearance granule combined with colon enema show satisfactory effect on CRF in aged patients as well as simple, practical and good compliance. This therapy is worth of spreading and putting into application.