摘要
目的观察一种复方邻苯二甲醛消毒剂的消毒性能。方法用载体定量和定性杀菌试验法,对该复方邻苯二甲醛消毒剂杀菌效果进行检测,用动物实验方法对其毒性作出评价。结果用含5.7 g/L邻苯二甲醛的该复方消毒剂对不锈钢载体上枯草杆菌黑色变种芽孢作用60 min,平均杀灭对数值>5.0;作用120 min,可达到完全杀灭。该复方邻苯二甲醛消毒剂对小鼠急性经口毒性试验LD50值>5000 mg/kg体重,小鼠骨髓嗜多染红细胞结果阴性。该邻苯二甲醛消毒剂原液密封包装,经54℃恒温存放14 d,其含量下降率为8.72%。结论该复方邻苯二甲醛消毒剂对细菌芽孢杀灭效果较好,属于无毒级物质,储存性能稳定。
Objective To observe the disinfection property of a compound orthophthalaldehyde disinfectant. Methods Carrier quantitative and qualitative germicidal tests were used to examine the germicidal efficacy of the compound orthoph- thalaldehyde disinfectant. Animal test method was used to evaluate the toxicity. Results The average killing logarithm val- ue of Bacillus subtilis var. niger spores on stainless steel carrier exposed to the disinfectant containing orthophthalaldehyde 5.7 g/L for 60 rain was 〉 5.0 and spores of Bacillus subtilis var. niger on the carrier exposed for 120 min were killed completely. LD50 of the oral acute toxicity of the disinfectant in mice was 〉 5000 mg/kg · bw. The result of mouse bone marrow polychromatic erythrocyte micronucleus test was negative. After storing in air - tight packing at 54℃ constant tem- perature for 14 d, its orthophthaladehyde cantent decreased by 8.72%. Conclusions The compound orthophthalaldehyde disinfectant has good efficacy in killing bacterial spores. It has no toxicity. It is stable during storage.
出处
《中国消毒学杂志》
CAS
2010年第1期17-19,22,共4页
Chinese Journal of Disinfection
关键词
邻苯二甲醛
杀菌效果
稳定性
毒性
orthophthalaldehyde
germicidal efficacy
stability
toxicity
