应变率显像评价尿毒症EF正常患者左心室局部功能

Evaluation of Left Ventricular Regional Systolic and Diastolic Function by Strain Rate Imaging in Uremic Patients with Normal Ejection Fraction

为探讨应变率显像(SRI)技术评价尿毒症左心室射血分数(EF)正常患者左心室局部功能的价值,对41例尿毒症EF正常患者及20例健康自愿者左心室心肌纵向SRI曲线进行分析,测量各曲线收缩峰值应变率(SRs)、舒张早期峰值应变率(SRe)、舒张晚期峰值应变率(SRa)并计算SRe/SRa。结果显示,尿毒症组左心室各节段SRs、SRe、SRe/SRa均低于对照组(P<0.05)。因此,尿毒症EF正常患者已经存在局部心肌舒缩功能障碍,并且这种障碍可以被SRI技术敏感、定量地评价。

To evaluate the left ventricular regional systolic and diastolic function by strain rate imaging（SRI） in uremic pa- tients with normal ejection fraction（EF）, left ventricle regional SRI curves of 41 uremic patients with normal EF and 20 healthy controls were analyzed. Peak systolic strain rate（SRs）, peak early diastolic strain rate（ SRe） and peak late diastolic strain rate（ SRa） values were measured,and SRe/SRa were calculated. Compared with controls, SRs,SRe and SRe/SRa of uremia decreased significantly（P〈0. 05）. Therefore, there have been regional systolic and diastolic abnormalities in uremic patients with normal EF,SRI can disclose these abnormalities sensitively and quantitatively.